Completed clinical study

Investigation of the activity of reward centers in the brain

A summary of the study results in layman’s terms will be published here shortly.

Original study description

We cordially invite you to participate in a clinical study at the University Hospital Zurich, which is investigating how reward is processed in the brain. Participation in the study is remunerated via the task (a reaction time game) in which money can be won. During a simple reaction time task, brain activity is recorded using electroencephalography (EEG), pupillometry and the heart rate using an electrocardiogram (ECG). The research laboratory where the study is being conducted is located at the ETH Technopark (Technoparkstrasse 1, 8005 Zurich).

Aim of the study

In our research project, we want to find out whether stroke patients have an altered activation of the reward areas of their brain in a motor task when rewarded compared to unaffected healthy controls and how this is reflected in the measurement of brain waves. In addition, it will be investigated how different feedback/rewards affect the learning of a motor task.

Who can take part?

We are looking for young adults (18-30 years old) without neurological or psychiatric conditions.

Procedure

The entire experiment requires one session per participant. Before the actual test begins, any questions and uncertainties are addressed. Various questionnaires are presented for completion and a cognitive screening is carried out. You will then be prepared for the EEG measurement: You will be fitted with an EEG cap with electrodes that record the brain waves. In addition, 3 electrodes are attached to your upper body to measure your heart rate. You will be placed in front of the computer so that your pupil size can be recorded. The task is to react as quickly as possible to a certain stimulus (image on the computer screen) by pressing a button. You will perform 3 blocks of exercises, between which you can take a break. The total duration of the experiment is approx. 90-120 minutes.

Compensation

Approx. 40 CHF, depending on your performance

Original study name

fMRI and EEG experiments to investigate the activity of reward centers during motor learning

BASEC number

2020-02608

Verwandte Krankheiten

Responsible Department