The severity of the bleeding tendency differs considerably depending on the type and subtype of VWS. Therefore, in addition to the basic diagnosis of VWS, it is always necessary to determine the type and subtype. In many cases, this requires highly specialized diagnostics, which is guaranteed in Switzerland by the cooperation of several university centers
The hemostasis laboratory at the Department of Hematology offers comprehensive diagnostics for suspected VWS:
- Antigen concentration and functional activity of the VWF
- Factor VIII activity
- Ristocetin-induced platelet agglutination
- VWF propeptide (turnover marker)
- Factor VIII binding capacity of the VWF
- After shipment to other centers: multimeric analysis, collagen binding activity of the VWF
