The clinical research group delves into the complexities of psoriasis, investigating treatment durability, gender differences in response, and underlying immunological mechanisms to improve patient outcomes in inflammatory skin diseases.
Our main research activities are focused on inflammatory skin diseases, with a particular emphasis on psoriasis, a highly stigmatizing disease that affects patients both physically and mentally, leading in most cases to poor quality of life and increased risk of severe comorbidities. Despite the highly efficacious treatment options since the introduction of specific therapies targeting key cytokines involved in the pathogenesis such as TNFα, IL-17 and IL-23, many clinical and immunological questions remain. Our goal is to investigating the drug survival of biologics and conventional systemics, sex and gender differences in treatment response and access to treatment, as well as the underlying immunological mechanisms involved.