Research Group: Cardiac Surgery (Prof. Dr. med. Dr. h.c. Omer Dzemali and PD Dr. med. Héctor Rodriguez Cetina Biefer)
The Cardiac Surgery Research Group is dedicated to advancing the field of cardiac surgery, particularly in the areas of minimally-invasive surgery, aortic diseases, and improving clinical outcomes. Our laboratory is committed to pushing the boundaries of medical innovation through a multidisciplinary approach, combining clinical expertise with basic science and engineering advancements
Minimally-Invasive Surgery and Aortic Diseases
Our research focuses on developing and refining minimally invasive surgical techniques to treat valvular, coronary, and aortic diseases. We aim to reduce patient trauma, improve recovery times, and enhance overall outcomes. We explore novel approaches to aortic repair and replacement, leveraging the latest medical technology and materials science advancements.
Immunomodulation and Ischemia Reperfusion Injury Prevention
In addition to our clinical focus, our laboratory is also engaged in basic science research on immunomodulation strategies to prevent ischemia-reperfusion injury and cardiotoxicity. We investigate the complex interplay between the immune system and cardiac tissue, seeking to develop therapeutic interventions that mitigate the adverse effects of cardiac surgery and improve patient outcomes.
Translational Research: Microbiome and Cardiac Surgery Outcomes
We are also at the forefront of translational research exploring the role of the microbiome in determining outcomes after cardiac surgery. Our research aims to elucidate the intricate relationships between the human microbiome, the immune system, and cardiac health, with a focus on identifying potential therapeutic targets to improve patient outcomes. By investigating the impact of the microbiome on post-operative recovery, we seek to develop novel strategies for personalized medicine and precision therapy in cardiac surgery.
Experimental Cardiac Surgery and Soft Robotics
In collaboration with the renowned Soft Robotics Lab at ETH Zurich, led by Prof. Robert Katzschmann, we are pioneering the application of soft robotics in experimental cardiac surgery. This innovative partnership enables us to explore the potential of soft robotics in cardiac interventions, such as developing novel, flexible, and adaptable surgical tools that can navigate complex cardiac anatomy with precision and delicacy.
Research Objectives
- Develop and refine minimally-invasive surgical techniques
- Investigate immunomodulation strategies to prevent ischemia reperfusion injury and cardiotoxicity
- Advance the field of experimental cardiac surgery through the integration of soft robotics
- Investigate the role of the microbiome in determining outcomes after cardiac surgery
- Improve clinical outcomes through evidence-based research and innovation.
Collaborative Environment
Our laboratory fosters a collaborative environment, bringing together clinicians, researchers, and engineers to tackle the most pressing challenges in cardiac surgery. We believe that interdisciplinary collaboration is key to driving meaningful progress and improving patient care.
Mission
Our mission is to transform the field of cardiac surgery through innovative research, education, and clinical practice, ultimately enhancing patients’ lives and advancing cardiovascular medicine.
