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Department of Angiology
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Research into rare vascular diseases

  • RAVE-T study (2021-02262): Clinical presentation, treatment and outcome of rare venous thrombosis and thromboembolism. This study is a retrospective analysis of patients with rare venous thrombosis (such as plantar vein thrombosis, ovarian vein thrombosis, renal vein thrombosis, mesenteric vein thrombosis, etc.) diagnosed, treated and followed up at the University Hospital Zurich. The primary aim of this retrospective study is to describe practice-based data from everyday clinical practice on the characteristics of the clinical presentation, treatment pattern and course of patients with rare venous thrombosis treated at the University Hospital Zurich over the last decade. Status: Analysis in progress.
  • BATTLE Registry: Bacterial-associated thrombosis/thrombophlebitis and Lemierre syndrome. BATTLE is a disease-specific, non-population-based, multicenter clinical registry with global reach and multidisciplinary scope specifically designed to address the limitations of current evidence and provide clinically relevant information to patients and physicians to improve the management and outcomes of patients with Lemierre syndrome and other forms of bacterial thrombophlebitis Sponsor: University of Mainz(https://www.unimedizin-mainz.de/battle-registry/uebersicht.html). Status: Approval pending.
  • Transient perivascular inflammation of the carotid artery (TIPIC) syndrome: an updated multinational analysis. TIPIC syndrome (Transient Perivascular Inflammation of the Carotid Artery) is characterized by a local, temporary inflammation of the tissue around the carotid artery. Its pathophysiology is still unknown. We conducted an update of TIPIC syndrome cases as part of a multinational study. Status: Published.
  • Clinical presentation and long-term follow-up of patients with Mondor’s disease (2020-00292). Status: Published.

Valentin ML*, Barco S, Studer G, Clemens RK, Kreuzpointner R, Sebastian T, Thalammer C, Kucher N. Prevalence of carotid plaque stenosis after head and neck radiotherapy. A prospective cohort study of 156 survivors. Vasa 2020; 49(6):467-473.

Barco S, Sollfrank S, Trinchero A, Adenaeuer A, Abolghasemi H, Conti L, Häuser F, Kremer Hovinga JA, Lackner KJ, Loewecke F, Miloni E, Shiran NV, Tomao L, Wuillemin WA, Zieger B, Lämmle B, Rossmann H. Severe plasma prekallikrein deficiency: Clinical characteristics, novel KLKB1 mutations, and estimated prevalence. J Thromb Haemost 2020; 18(7):1598-1617.

Valerio L, Zane F, Sacco C, Granziera S, Nicoletti T, Russo M, Corsi G, Holm K, Righini C, Karkos PD, Mahmoudpour SH, Kucher N, Verhamme P, Di Nisio M, Centor RM, Konstantinides SV, Pecci A, Barco S. Patients with Lemierre syndrome have a high risk of new thromboembolic complications, clinical sequelae and death: an analysis of 712 cases. Journal Internal Medicine 2020; 289(3):325-339.

Micieli E, Voci D, Mumoli N, Mastroiacovo D, Grigorean A, Obadia M, de Champfleur NM, Naggara O, Carsin B, Amor-Sahli M, Cottier JP, Bensoussan J, Auffray-Calvier E, Varoquaux A, Bonneville F, Sadik JC, Kucher N, Lecler A, Barco S*. Transient perivascular inflammation of the carotid artery (TIPIC) syndrome. Vasa 2022 Feb 8. doi: 10.1024/0301-1526/a000989.

Kreuzpointner R, Johner F, Roth-Zetzsche S, Kucher N, Barco S*. Clinical presentation and long-term follow-up of 45 patients with Mondor disease: A single-center longitudinal study. Vascular med 2021; 1358863X211000420.