In this study, ultrasound- or mammography-guided vacuum-assisted biopsy is used to detect residual tumor lesions in patients with radiologically complete response (rCR) after neoadjuvant chemotherapy. The investigators will evaluate the diagnostic accuracy of the vacuum-assisted biopsy after neoadjuvant chemotherapy compared to the sample obtained in open surgery.
Aim of the study
The main objective of the study is to determine the diagnostic accuracy of vacuum-assisted biopsy using complete pathologic specimen evaluation obtained after open surgery to detect residual tissue.
Who can take part?
Patients with breast cancer
Procedure
In this study, ultrasound (US) or mammography (MG) guided vacuum-assisted biopsy is used to detect residual tumor lesions in patients with radiologically complete response (rCR) after neoadjuvant chemotherapy. The investigators will evaluate the diagnostic accuracy of the vacuum-assisted biopsy after neoadjuvant chemotherapy compared to the sample obtained in open surgery.
Compensation
Original study name
Intelligent Vacuum assisted biopsy Immediately before Surgery as an Intra- or pre-Operative surrogate for patient response to Neoadjuvant chemotherapy for breast cancer (VISION I). A multicenter prospective feasibility trial
BASEC number
2020-00450
Financial support from
Hirslanden