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Portrait Dorothea Rosenberger, Ph.D.

Dorothea Rosenberger, Ph.D.
Prof. Dr. med.

Senior Attending Physician, Institute of Anesthesiology

Specialties

  • Anesthesiology and intensive care medicine
  • Global Health / Humanitarian action projects

Departments

Contact

Tel. +41 44 255 11 11

Career

Academic career

since 2018 Professor of Anesthesiology and Critical Care Medicine, University of Utah Medical School, Salt Lake City, Utah, U.S.A.
2014 – 2018 Associate Professor of Anesthesiology and Critical Care Medicine, University of Utah Medical School, Salt Lake City, Utah, U.S.A.
2010 – 2014 Associate Professor of Anesthesiology and Critical Care Medicine, Adjunct Associate Professor of Neurosurgery, Medical University of South Carolina (MUSC), Charleston, South Carolina, U.S.A.
2005 – 2010 Assistant Professor of Anesthesiology and Critical Care Medicine, University of Louisville, Louisville, Kentucky, U.S.A.
2009 PhD in Cardiovascular Physiology, Department of Biophysics and Physiology, University of Louisville, Louisville, KY, U.S.A.
2005 Diploma European Society of Anesthesiology and Intensive Care
2003 – 2004 Cardiac surgery intensive care unit and cardiac anesthesia at the University Hospital Zurich, Switzerland
2001 – 2005 Specialist training,resident in anesthesiology, emergency medicine (Rega) and intensive care medicine at the University Hospital Zurich, Switzerland
1998 – 2001 Specialist training, resident in emergency medicine, anesthesiology, burns & trauma intensive care at the Berufsgenossenschaftliche Unfallklinik, Ludwigshafen, Germany
2000 Doctorate Dr. med., Ruprecht-Karls University Heidelberg, Germany
1997 Study fellowship in surgery, Memorial Sloan Kettering Cancer Center, New York City, NY, U.S.A.
1996 Study visit in anesthesiology, Tenerife, Islas Canarias, Spain
1996 – 1997 Study of human medicine (practical year) Albert-Ludwigs-University Freiburg, Germany
1991 – 1996 Studied human medicine at Ruprecht-Karls-Universität Heidelberg, Germany

Global Health/Humanitarian action projects

2021 Medical Mission Team, Migori, Kenya
2020 COVID-ICU Medical Team at New York Presbyterian Hospital, New York City, NY, U.S.A.
2012 Visiting Professor and Medical Mission Team, University of Health Sciences, Phnom Penh and Angkor Hospital for Children, Siem Reap, Cambodia
2009 Medical Mission Team, Pokhara, Nepal
2008 Medical Mission Team, Manila, Philippines
2000 – 2005 Aiut Alpin Dolomites, Mountain Rescue, Pontives, Italy
1991 – 1996 Amnesty International Student Group, University of Heidelberg, Germany

Memberships

  • German Society for Anaesthesia and Intensive Care Medicine (DGAI)
  • Association of German Anaesthetists (BDA)
  • International Anesthesia Research Society (IARS)
  • European Society of Anesthesiology and Intensive Care (ESAIC)
  • American Society of Anesthesiologists (ASA)
  • Society of Critical Care Anesthesiologists (SOCCA)
  • Society for Neuroscience in Anesthesiology and Critical Care (SNACC)
  • Neurocritical Care Society (NCS)
  • Heidelberg Medical School Alumni Germany and United States (HAUS)
  • 2017-2021 Chairperson ASA American Society of Anesthesiology Committee on Neuroanesthesia (member since 2014)
  • Since 2016 Committee Member, ASA American Society of Anesthesiology, Committee on Critical Care Medicine
  • 2020 ASA president appointed member of Ad hoc ASA Committee on Life Imbalances
  • Reviewer for “PLoS One”, Publisher Public Library of Science
  • Reviewer for “Journal of Surgical Research”

Research focus

  • Since 2018 Principal Investigator Identification of a phenotype for increased risk of haemorrhage in ECMO, LVAD/RVAD and septic patients (IRB approval # 00110290, University of Utah Grant supported
  • 4/2020-4/2021 Principal Investigator Assessment of Patient Characteristics and Treatment Strategies from Critical Coronavirus-2019 Infections (COVID19). Grant supported Immunology, Inflammation, and Infectious Diseases 3i Initiative University of Utah Medical School
  • 2012-2014 Principal Investigator and co-PI on NIH 5R01AG044920-02 with total costs of $264,000.00 plus additional intramural grant support Mechanisms of anesthetics in a rodent model, collaboration with Neurosciences, PI Ann-Charlotte Granholm, D.D.S., Ph.D. (Colorado University Anschutz, Denver, Colorado, U.S.A.)

  • The value of open-source clinical science in pandemic response: lessons from ISARIC
    ISARIC Clinical Characteristics Group(Rosenberger D, Site-PI)
    Lancet Infectious Disease 2021 Dec;21(12): 1623-1624
  • Ten months of temporal variation in the clinical journey of hospitalized patients with COVID-19: An observational cohort.
    ISARIC Clinical Characterization Group,(Rosenberger D, Site-PI),
    Elife 2021 Nov23;10e70970, PMID:34812731
  • COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study
    ISARIC Clinical Characteristics Group(Rosenberger D, Site-PI)
    Infection 2021 Oct;49(5):889-905
  • Hilton EJ, Lunardi N, Sreedharan R, Goff KL, Batakji and Rosenberger DS. Two sides of the same coin: addressing racial and gender disparities among physicians and the impact on the community they serve. Anesthesiology Clinics 2020(38): 369-377
  • Hilton EJ, Lunardi N, Sreedharan R, Goff KL, Batakji and Rosenberger DS.The flaw of medicine: addressing racial and gender disparities in critical care. Anesthesiology Clin 2020 (38):357-368
  • Sidhu SK, Weavil JC, Thursdon TS, Rosenberger D, Jessop JE, Wang E, Richardson RS, McNeil CJ, Amann M.
    Fatigue-related group III/IV muscle afferent feedback facilitates intracortical inhibition during locomotor exercise
    J Physiology 2018;596.19:4789-4801
  • Rosenberger DS, Falangola FM, Ledreaux A, Nie X, Suhre W, Boger H, and Granholm AC
    Memory and hippocampal architecture following short-term midazolam in western diet-treated rats. Neurosciences Letters 2016 May 16;621:68-74
  • Rosenberger D, Gargoum R, Tyagi N, Metreveli N, Sen U, Maldonado C, and Tyagi S. Homocysteine enriched diet leads to prolonged QT interval and reduced left ventricular performance in telemetric monitored mice. Nutr Metab Cardiovasc Dis 2011 Jul;21(7):492-8
  • Maldonado C, Soni CV, Todnem ND, Pushpakumar S, Rosenberger D, Givvimani Villafane J, Tyagi SC. Hyperhomocysteinemia and sudden cardiac death: potential arrhythmogenic mechanisms. Current Vasc Pharmacol, January 2010; 8(1):64-74
  • Hughes WM Jr, Rodriguez WE, Rosenberger D, Chen J, Sen U, Tyagi N, Moshal KS, Vacek T, Kang YJ, Tyagi SC.Role of Copper and Homocysteine in Pressure Overload Heart Failure. Cardiovasc Toxicol. 2008 Fall;8(3):137-44
  • Moshal KS, Zeldin DC, Sithu SD, Sen U, Tyagi N, Kumar M, Hughes WM Jr, Metrveli N, Rosenberger DS, Singh M, Vacek TP, Rodriguez WE, Ayotunde A, Tyagi SC. Cytochrome P450(CYP) 2J2 gene transfection attenuates MMP-9 via inhibition of NF-kappabeta in hyperhomocysteinemia. J Cell Physiol. 2008 Jun;214(3):771-81
  • Tyagi N, Lominadze D, Gillespie W, Moshal KS, Sen U, Rosenberger DS, Steed M, and Tyagi SC. Differential expression of gamma-aminobutyric acid receptor A (GABA(A)) and effects of homocysteine. Clin Chem Lab Med. 2007;45(12):1777-84
  • Sen U, Tyagi N, Moshal KS, Kartha GK, Rosenberger DS, Henderson BC, Joshua IG, Tyagi SC. Cardiac synchronous and dys-synchronous remodeling in diabetes mellitus. Antioxid Redox Signal. 2007 Jul;9(7):971-8.
  • Rosenberger DS, Moshal KS, Kartha GK, Tyagi N, Sen U, Lominadze D, Maldonado C, Roberts A, Tyagi SC. Arrhythmia and neuronal/endothelial myocyte uncoupling in hyperhomocysteinemia. Archives Physiol Biochem. 2006 Dec;112(4-5):219-227.
  • Moshal KS, Singh M, Sen U, Rosenberger DS, Henderson B, Tyagi N, Zhang H, Tyagi SC. Homocysteine-mediated activation and mitochondrial translocation of calpain regulates MMP-9 in MVEC. Am J Physiol Heart Circ Physiol. 2006 Dec;291(6):H2825-35.
  • Beck Schimmer B, Rosenberger DS, Neff SB, Jamnicki M, Furrer T, Booy C, Reyes L, Pasch T, Schimmer RC. Pulmonary Aspiration: New therapeutic approaches in the experimental model. Anesthesiology. 2005;103:556-66.